Fisetin and Asthma: What the Airway Research Shows
In mice with allergic asthma, fisetin calmed airway inflammation and twitchy airways. No person with asthma has been studied. Here is what the research shows.
A Blood Test for Senescent Cells? The C12FDG Study and Fisetin
A 2024 Aging Cell study counted senescent white blood cells with C12FDG. The count rose with age and fell in a small group taking fisetin.
The Low-Dose Fisetin Trial: 100 mg a Day, Seven Weeks, and suPAR
A triple-blind trial will give adults over 50 just 100 mg of fisetin a day for seven weeks. What it measures, why, and what it cannot tell you yet.
Fisetin and Thyroid Function: What the Enzyme Inhibition Data Actually Means
Two papers, from 1996 and 2002, name fisetin as an inhibitor of thyroid enzymes. Neither is obscure, both are indexed
Fisetin and Uric Acid: The URAT1 Finding and the Xanthine Oxidase Myth
Fisetin was the most potent URAT1 inhibitor in a screen of dietary flavonoids, beating quercetin. That is a real finding, and it is not the mechanism most articles claim it has.
Fisetin and Lung Health: What the Pulmonary Fibrosis Research Actually Shows
One mouse study found fisetin reduced lung fibrosis. Another found it wasn’t much help. And fisetin failed to kill senescent human lung fibroblasts in the study that discovered it was senolytic. The full picture is messier than the headline.
Fisetin, COVID-19, and Post-Viral Senescence: What the Clinical Trial Data Actually Shows
A federally funded trial tested fisetin in COVID-positive nursing home residents. It didn’t test long COVID, and no dedicated fisetin long-COVID trial exists. Here’s the real research, not the version that gets shared online.
Fisetin for Women Over 50: How Senolytic Research Applies to Perimenopause and Postmenopause
Fisetin’s senescent-cell-clearing mechanism touches ovarian aging, bone loss, and hormonal decline, all central to perimenopause. Here’s what the preclinical research shows, and why no human trial has tested it yet.
Where to Buy Fisetin Supplements: Amazon, iHerb, and Direct Brands Compared
Comparing Amazon, iHerb, and direct-brand purchasing for fisetin supplements: quality signals, pricing, and what to look for before you buy.
Fisetin vs. Spermidine for Longevity: Comparing Senolytic and Autophagy-Inducing Mechanisms
How do fisetin and spermidine differ as longevity compounds? An evidence-based comparison of senolytic and autophagy-inducing pathways for healthy aging.
Fisetin vs NMN: Two Different Pathways to Healthy Aging
Fisetin targets senescent ‘zombie’ cells; NMN restores NAD+ and cellular energy. An honest comparison of the evidence behind both longevity supplements.
Fisetin Side Effects and Safety Profile: What the Evidence Actually Shows
A clear-eyed look at fisetin side effects, drug interactions, and the significant gaps in human safety data for this senolytic flavonoid.