Fisetin shrinks infarct size in rodent stroke models with unusual consistency across labs. It is also one of the areas where the gap between an animal model and a real emergency is widest.
Fisetin improved fatty liver in mice across several models, but almost every study injected it rather than feeding it, and no human trial has tested it for liver disease. Here’s what that actually means.
Age-related macular degeneration (AMD) is the leading cause of vision loss in older adults in Western countries, and researchers increasingly
Osteoarthritis is, at its core, a disease of cartilage breakdown, and a growing body of research has identified senescent chondrocytes
Fisetin is a plant flavonoid studied as a senolytic agent. Learn what the research actually shows—and where the evidence still falls short.
Fisetin and resveratrol are both studied for longevity, but their evidence bases look quite different. Here’s an honest comparison.
Learn why third-party HPLC testing is essential for fisetin supplements, what a certificate of analysis should show, and red flags to avoid.
Fisetin is studied as a senolytic targeting ‘zombie’ cells. Here’s an honest look at what mouse research shows—and what remains unknown in humans.
A close look at the landmark 2018 EBioMedicine study on fisetin, senescent cells, and lifespan extension in mice—what it found and what it means for humans.
Can the senolytic flavonoid fisetin shift your biological age? A careful look at DNA methylation clock research, honest findings, and real limitations.
Fisetin is generally considered low-risk for most healthy adults at the doses studied in research, but the honest answer is
As we navigate the complexities of aging, a persistent question remains: can we not just extend our lifespan, but enhance