Fisetin and Epilepsy: What the Seizure Research Shows
Fisetin raised seizure thresholds and slowed kindling in rodent epilepsy models. It has never been tested in people with epilepsy. Here is the evidence.
Fisetin and Prostate Cancer: What the Research Shows
Fisetin killed prostate cancer cells and boosted cabazitaxel in mice. No trial has tested it in men. Here is what the lab studies found.
Can High-Dose Fisetin Damage DNA? What the Cell Studies Show
At 40 to 80 micromolar, fisetin breaks DNA in cancer cells. Here is what that means, and how far it sits above anything a supplement puts in your blood.
Fisetin Plus Exercise in Men With Obesity: Two Papers, Probably One Trial
Two 2026 trials tested fisetin with resistance training in men with obesity. The results are real, and the two papers are almost certainly one study.
Fisetin and Rheumatoid Arthritis: Why the Osteoarthritis Evidence Does Not Transfer
Search for fisetin and arthritis and you will get results about joint pain, cartilage and senescent cells. Almost all of
Fisetin and Gum Disease: What the Periodontitis Research Actually Shows
Periodontitis is a strange fit for a longevity supplement, and also a surprisingly logical one. It is a chronic inflammatory
Fisetin, Testosterone, and Male Fertility: What the Research Actually Shows
Fisetin raised testosterone and restored sperm counts in rats, but every one of those studies first poisoned the animals. When researchers tested fisetin in healthy animals and measured actual fertility, they found nothing.
Fisetin and Nerve Pain: The Neuropathy Research and a Real Interaction Concern
Fisetin reduced nerve pain in diabetic and chemotherapy-induced neuropathy models. It also made gabapentin, pregabalin and opioids work harder, which is the part that matters if you already take one of them.
Fisetin and Hair Growth: Why the TERT Research Doesn’t Mean Capsules Regrow Hair
Fisetin triggered hair regrowth on shaved mice by boosting TERT in skin cells. The detail that gets dropped from every summary: it was applied to the skin, not swallowed.
Fisetin and Kidney Health: What Preclinical Research Shows About Renal Fibrosis
Across four different mouse models of kidney injury, fisetin consistently reduced senescent cell burden and fibrosis. But one study found no improvement in actual kidney function. Here’s what that gap means.
Fisetin Liposomal and Phytosomal Formulations: Do Enhanced Delivery Systems Justify the Price?
Standard fisetin has notoriously poor bioavailability. Liposomal and phytosomal versions promise better absorption — here’s what the actual pharmacokinetic data says.
Taking Fisetin With Fat: How Meal Composition Affects Absorption
Fisetin is poorly water-soluble. Learn why pairing it with dietary fat may improve absorption, what timing research suggests, and who should be cautious.